Barry Crook Selected Research

6- ((3- cyclobutyl- 2,3,4,5- tetrahydro- 1H- 3- benzazepin- 7- yl)oxy)- N- methyl- 3- pyridinecarboxamide

12/2013	Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonists.
6/2007	GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Barry Crook Research Topics

Disease

3	Dementia (Dementias) 12/2013 - 04/2007
2	Alzheimer Disease (Alzheimer's Disease) 12/2013 - 06/2007
1	Cognitive Dysfunction 06/2007
1	Neuralgia (Stump Neuralgia) 04/2007
1	Amnesia (Dissociative Amnesia) 04/2007
1	Hyperalgesia 04/2007
1	Stroke (Strokes) 01/2006
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2006

Drug/Important Bio-Agent (IBA)

2	6- ((3- cyclobutyl- 2,3,4,5- tetrahydro- 1H- 3- benzazepin- 7- yl)oxy)- N- methyl- 3- pyridinecarboxamideIBA 12/2013 - 06/2007
2	Histamine H3 Receptors (Histamine H3 Receptor)IBA 12/2013 - 06/2007
1	GSK239512IBA 12/2013
1	Cholinergic Antagonists (Anticholinergics)IBA 04/2007
1	1- (1- methylethyl)- 4- ((1- (6- (trifluoromethyl)- 3- pyridinyl)- 4- piperidinyl)carbonyl)hexahydro- 1H- 1,4- diazepineIBA 04/2007
1	Capsaicin (Zostrix)FDA Link 04/2007
1	5- ((3- cyclobutyl- 2,3,4,5- tetrahydro- 1H- 3- benzazepin- 7- yl)oxy)- N- methyl- 2- pyrazinecarboxamideIBA 04/2007
1	Scopolamine (Hyoscine)FDA Link 04/2007
1	Histamine H3 AntagonistsIBA 04/2007
1	Messenger RNA (mRNA)IBA 01/2006

Therapy/Procedure

1	Therapeutics 12/2013